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First named in Scripture at Genesis 41:52 — read the chapter.

From Easton’s Bible Dictionary (1897)

double fruitfulness (“for God had made him fruitful in the land of his affliction”). The second son of Joseph, born in Egypt (Genesis 41:52; 46:20). The first incident recorded regarding him is his being placed, along with his brother Manas seh, before their grandfather, Jacob, that he might bless them (48:10; comp. 27:1). The intention of Joseph was that the right hand of the aged patriarch should be placed on the head of the elder of the two; but Jacob set Ephraim the younger before his brother, “guiding his hands wittingly.” Before Joseph’s death, Ephraim’s family had reached the third generation (Genesis 50:23).

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