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First named in Scripture at Acts 20:4 — read the chapter.

From Easton’s Bible Dictionary (1897)

a foster-child, an Ephesian who accompanied Paul during a part of his third missionary journey (Acts 20:4; 21:29). He was with Paul in Jerusalem, and the Jews, supposing that the apostle had brought him with him into the temple, raised a tumult which resulted in Paul’s imprisonment. (See TEMPLE, HEROD’S.) In writing to Timothy, the apostle says, “Trophimus have I left at Miletum sick” (2 Timothy 4:20). This must refer to some event not noticed in the Acts.

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